Modifying Enzymes
Medchemexpress LLC HY-110115 10mg Medchemexpress, TC-Mps1-12 CAS:1206170-62-8 Purity:>98%
Medchemexpress, HY-110115 10mg TC-Mps1-12 CAS:1206170-62-8 TC-Mps1-12 is a potent and selective monopolar spindle 1 (Mps1) inhibitor, with an IC50 of 6.4 nM. Purity:>98% Medchemexpress has over 10000 novel life-science reagents, reference compounds, APIs and natural compounds for laboratory and scientific use. Other quantity can also be offered.
Cayman Chemical Decnoyl-Coenzyme Ahydrate 10mg
A thioester of decanoic acid and CoA; inhibits the activity of mitochondrial CS and GDH isolated from rat brain (IC50s = 437 and 420 µM, respectively); inhibits FadR from binding its promoter in E. coli (Ki = 2 µM); produced during isomerase-dependent β-oxidation of oleic acid in isolated rat heart mitochondria
New England Biolabs, Inc. Cre Recombinase – 250 units
Cre Recombinase is a Type I topoisomerase from bacteriophage P1 that catalyzes the site-specific recombination of DNA between loxP sites. The enzyme requires no energy cofactors and Cre-mediated recombination quickly reaches equilibrium between substrate and reaction products. The loxP recognition element is a 34 base pair (bp) sequence comprised of two 13 bp inverted repeats flanking an 8 bp spacer region which confers directionality. Recombination products depend on the location and relative orientation of the loxP sites. Two DNA species containing single loxP sites will be fused. DNA between directly repeated loxP sites will be excised in circular form while DNA between opposing loxP sites will be inverted with respect to external sequences.
![Amsbio LLC Neuraminidase [Sialidase]; Acylneuraminyl hydrolase [EC 3.2.1.18]](https://assets.fishersci.com/TFS-Assets/CCG/product-images/502566247.png-250.jpg)
Amsbio LLC Neuraminidase [Sialidase]; Acylneuraminyl hydrolase [EC 3.2.1.18]
Neuraminidase [Sialidase]; Acylneuraminyl hydrolase [EC 3.2.1.18]
Apexbio Technology LLC T7 Endonuclease I(Synonyms: T7EI, T7 Endo I, T7 Endonuclease 1, T7 Endo 1, T7 mismatch-specific endonuclease), 250U.
T7 Endonuclease I (T7EI) is a recombinant DNA endonuclease produced through expression in E coli T7EI specifically targets and cleaves diverse forms of DNA substrates containing structural anomalies including mismatches of at least two base pairs heteroduplex DNA cruciform structures Holliday junctions and branched DNA intermediates as well as nicked duplexes at reduced cleavage efficiency It hydrolyzes phosphodiester bonds located near mismatched nucleotides 5 ends This enzyme is widely employed in detecting genetic mutations induced by gene-editing systems (e g CRISPR/Cas9 TALENs) identifying single nucleotide polymorphisms (SNPs) and generating randomized DNA fragments for shotgun cloning techniques
Cayman Chemical Oleoyl-L-carnItIn-d3chlorI 5mg
An internal standard for the quantification of oleoyl-L-carnitine by GC- or LC-MS
Enzo Life Sciences SP600125, (10mg), CAS Number: 129-56-6
Jnk inhibitor. Potent, cell permeable, selective, and reversible inhibitor of c-Jun N-terminal kinase (JNK) (IC50=40nM for JNK-1 and JNK-2 and 90nM for JNK-3). The inhibition is competitive with respect to ATP. Exhibits over 300-fold greater selectivity for JNK as compared to ERK1 and p38. Inhibits the phosphorylation of c-Jun and blocks the expression of IL-2, IFN-γ, TNF-α, and COX-2. Blocks IL-1-induced accumulation of phospho-Jun, induction of c-Jun transcription and anti CD3-induced apoptosis of CD4+ CD8+ thymocytes. Alternative Name: Anthra(1,9-cd)pyrazol-6(2H)-one, 1,9-Pyrazoloanthrone. Formula: C14H8N2O. MW: 220.2. CAS Number: 129-56-6. Purity: ≥98% (TLC). Appearance: Yellow to brown solid. Solubility: Soluble in DMSO or methanol. Use/Stability: Stable for at least 1 year after receipt when stored at +20°C. Stock solutions are stable for up to 3 months at -20°C. Long Term Storage: Ambient
EPICYPHER INC CUTANA™ pAG-MNase for ChIC/CUT&RUN Workflows - 50 rxns
CUTANA™ pAG-MNase for ChIC/CUT&RUN Workflows - 50 rxns
STEMCELL Technologies ArciTect Cas9-eGFP Nuclease , Size: 100 ug
Enhanced green fluorescent protein (eGFP)-tagged Cas9 nuclease (3 μg/ul) for the generation of double-strand breaks in CRISPR-Cas9 genome editing
Amsbio LLC Chondroitinase AC-I (EC 4.2.2.5) from Flavobacterium heparinum/ 5IU
Chondroitinase AC-I (EC 4.2.2.5) from Flavobacterium heparinum 5IU
STEMCELL Technologies DNase I, ACF, Size: 100000 U
Deoxyribonuclease I (DNase I), Animal Component-Free (ACF) is obtained from cultures free of animal-derived materials and purified by chromatography. DNase I is an endonuclease consisting of a single glycosylated polypeptide chain with two disulfide bonds. DNase is often included in tissue dissociation protocols to digest DNA that has leaked into the dissociation medium as a result of cell damage. DNase I, ACF preferentially cleaves phosphodiester linkages adjacent to pyrimidine nucleotides in both single- and double-stranded DNA, yielding polynucleotides with 5’-phosphate and 3’-hydroxyl groups (Bernardi et al.). DNase I has been used for the digestion of human tissues such as microglia (Klegeris & McGeer), cartilage (Dunham & Koch), colon (Fukushima & Fiocchi), epithelium l (Fukushima & Fiocchi), liver (Vatakis et al.), lung (Fujino et al.), neural (Fuja et al.), and stem cells (Kusuma et al.).
Worthington Biochemical Corporation DEOXYRIBONUCLEASE II 80KU
A dialyzed, lyophilized powder. 9025-64-3
INTACT GENOMICS INC T4 DNA Ligase 100,000 Units (2000 units/µl)
Intact Genomics T4 DNA Ligase catalyzes the formation of a phosphodiester bond between juxtaposed 5’-phosphate and 3’-hydroxyl termini in duplex DNA or RNA. This enzyme joins DNA fragments with either cohesive or blunt termini and repairs single stranded nicks in duplex DNA, RNA or DNA/RNA hybrids (1).Applications• Cloning of restriction enzyme generated DNA fragments• Cloning of PCR products• Next-gen library preparation• Joining linkers and adapters to cohesive or blunt-ended DNA• Nick repair in duplex DNA, RNA or DNA/RNA hybrids• Self-circularization of linear DNA